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Four fun-loving girls are set to shake things up on Trouble this week as the smash-hit comedy drama No Angels makes its debut. Set amid the hectic wards of St Margaret’s hospital in Leeds, No Angels follows the lives of four nurses who just can’t get enough of each other – they work together, socialise together and even share a house.

Facing life, death and unruly patients on a daily basis these women are out for fun as soon as they clock off, meaning boozy nights, uncomplicated sex and general misbehaviour are all on the cards. Anji (Sunetra Sarker) has her heart set on an arranged marriage, while Beth (Jo Joyner) longs for a rich consultant to sweep her off her feet. None of this stops them having fun though; after all, they do have to practice their bedside manner.

Lia (Louise Delamere) is a single mum and often finds juggling her work and home life tricky, while Kate (Kaye Wragg) is banking on being promoted to Acting Sister, a role which would see her stretched to her limits, especially as she still needs to find time to conduct her complex love life.

On Monday, Kate has a one-nightstand with handsome doctor Jamie. As well as being totally out of character, Kate’s night of passion has far reaching consequences for the ward when Jamie makes a mistake and discharges a seriously ill patient, only to blame his lapse in judgement on Kate.

Elsewhere, Beth decides to show Callum that doctors don’t always know best. Later this week, Anji starts to worry that her carefree attitude – especially when it comes to her mounting number of sexual conquests – might jeopardise her arranged marriage, while nonmaternal mum Lia struggles to find time for her daughter.

Starring four cheeky minxes who are the of the very embodiment of naughty nurses, No Angels is the perfect reason to stay in this week.